Identifying Common Genetic Risk Factors of Diabetic Neuropathies

Identifying Common Genetic Risk Factors of Diabetic Neuropathies

Type 2 diabetes mellitus (T2DM) is a global public health problem of epidemic proportions, with 60-70% of affected individuals suffering from associated neurovascular complications that act on multiple organ systems. The most common and clinically significant neuropathies of T2DM include uremic neuropathy, peripheral neuropathy, and cardiac autonomic neuropathy. These conditions seriously impac...

Identifying genetic risk factors for osteoporosis.

Over the past decades epidemiological research of so-called "complex" diseases, i.e., common age-related disorders such as cancer, cardiovascular disease, diabetes, and osteoporosis, has identified anthropometric, behavioural, and serum parameters as risk factors. Recently, genetic polymorphisms have gained considerable interest, propelled by the Human Genome Project and its sequela that have i...

Organizing Prenatal Care and Identifying Risk Factors

هنگامی حاملگی پرخطر در نظر گرفته می شود که احتمال سرانجام بد برای مادر و نوزاد نسبت به زنان حامله عادی بیشتر باشد. اکثر حاملگی ها براساس این تعریف پرخطر نمی باشند.

Identifying Genetic Risk Factors in Canine Autoimmune Disorders

Diabetic somatic neuropathies.

SECTION 1: INTRODUCTION — The neuropathies are among the most common of the long-term complications of diabetes, affecting up to 50% of patients (1–4). Their clinical features vary immensely, and patients may present to a wide spectrum of specialties, from dermatology to podiatry, for example, or from urology to cardiology. Neuropathies are characterized by a progressive loss of nerve fibers, w...